Neurodivergent Workplace Strategist & Culture Creator; Burnout Prevention Expert; Co-Host of the "Divergent Conversations" Podcast & Author of "So You're Autistic...Now What?"

Asheville, NC, USA

Patrick Casale Biography

Patrick Casale is a TEDx speaker, keynote presenter, consultant, and thought leader whose work explores late-in-life Autism discovery, leadership, workplace culture, and the often-hidden cost of self-doubt.

Casale’s TEDx talk on discovering Autism in adulthood stands as a defining moment in his speaking career. Through deeply personal storytelling and clinical insight, he illuminated what it means to grow up undiagnosed, to learn how to mask in order to survive, and to later untangle identity, burnout, and belonging as an adult. His talk resonated widely for its honesty and clarity—giving language to experiences many people had lived but never heard named.

As a speaker, Casale brings a rare combination of lived experience, professional expertise, and executive-level leadership. He delivers keynotes and trainings for conferences, organizations, and leadership teams across the U.S. and internationally, helping audiences rethink neurodivergence, productivity, and performance through a more humane and inclusive lens. His work challenges systems that reward over-functioning and quiet suffering, while offering practical pathways toward psychological safety, sustainable leadership, and neurodivergent-affirming cultures.

Casale is the host of two globally recognized podcasts, All Things Private Practice and Divergent Conversations, where he has facilitated hundreds of conversations on Autism, ADHD, identity, leadership, entrepreneurship, and mental health. Across these platforms, he has become a trusted voice for professionals and leaders navigating late diagnosis, burnout, and the tension between success and self-abandonment.

He is also the author of an upcoming book focused on late-in-life Autism discovery, identity reconstruction, and the emotional aftermath of finally understanding your nervous system after decades of misattunement. The book extends the core themes of his TEDx talk—grief, relief, self-doubt, and self-trust—while offering readers language, validation, and hope.

Casale’s speaking style is authentic, disarming, and story-driven. He blends vulnerability, humor, and insight to create spaces where people feel seen without being pathologized. Whether addressing clinicians, executives, entrepreneurs, or organizational leaders, his message is consistent: self-doubt is not a flaw, neurodivergence is not a deficit, and leadership begins when we stop forcing people—including ourselves—to perform inside systems that were never built for us.

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Speaker profile last updated by AAE Talent Team on 01/13/2026.

Patrick Casale Speaking Topics

  • Doubt Yourself, Do It Anyway: Leading Through Fear, Uncertainty, and Change

    Self-doubt, fear of failure, and uncertainty are not signs of weakness—they are natural companions to meaningful leadership and innovation. In this talk, Patrick Casale reframes doubt as a catalyst rather than an obstacle. Drawing from his experience as a therapist, entrepreneur, and speaker, he explores how leaders can take aligned risks, navigate discomfort, and make values-based decisions even when clarity is missing. This session challenges hustle culture and perfectionism while offering practical tools for moving forward without waiting for confidence to arrive. Attendees leave with a grounded framework for courageous leadership, sustainable momentum, and authentic impact—especially during times of rapid change and burnout.

  • Neurodiversity at Work: Building Inclusive, Human-Centered Organizations

    Neurodivergent individuals (Autistic, ADHD, AuDHD, dyslexic, highly sensitive, and more) are deeply embedded in today’s workforce—often without adequate support or understanding. This session introduces a neurodiversity-affirming lens to leadership, culture, and workplace design. Patrick Casale explores common systemic barriers, the cost of masking and burnout, and how organizations can move beyond performative inclusion toward meaningful accessibility. Leaders will learn how to build environments that support diverse thinking styles, communication needs, and sensory differences—resulting in stronger retention, innovation, and psychological safety. This talk is ideal for organizations seeking to align values with action.

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Patrick Casale Videos

Patrick Casale | TEDxManitouSprings

Patrick Casale | TEDxManitouSprings

Lessons from a late in life autism discovery

  • How do I book Patrick Casale to speak at my event?

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  • What are the speaker fees for Patrick Casale

    Speaking fees for Patrick Casale, or any other speakers and celebrities, are determined based on a number of factors and may change without notice. The estimated fees to book Patrick Casale are $10,000 - $20,000 for live events and $10,000 - $20,000 for virtual events. For the most current speaking fee to hire Patrick Casale, click the Check Availability button above and complete the form on this page, or call our office at 1.800.698.2536 to speak directly with an experienced booking agent.
  • What topics does Patrick Casale speak about?

  • Where does Patrick Casale travel from?

    Patrick Casale generally travels from Asheville, NC, USA, but can be booked for private corporate events, personal appearances, keynote speeches, or other performances. For more details, please contact an AAE Booking agent.
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    AAE Speakers Bureau has successfully booked keynote speakers like Patrick Casale for clients worldwide since 2002. As a full-service speaker booking agency, we have access to virtually any speaker or celebrity in the world. Our agents are happy and able to submit an offer to the speaker or celebrity of your choice, letting you benefit from our reputation and long-standing relationships in the industry. Please click the Check Availability button above and complete the form on this page including the details of your event, or call our office at 1.800.698.2536, and one of our agents will assist you to book Patrick Casale for your next private or corporate function.
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Patrick Casale is a keynote speaker and industry expert who speaks on a wide range of topics such as Doubt Yourself, Do It Anyway: Leading Through Fear, Uncertainty, and Change, Neurodiversity at Work: Building Inclusive, Human-Centered Organizations, Beyond Burnout: Redefining Success Without Sacrificing Your Well-Being, Late Identification & Identity: The Impact of Discovering Who You Really Are and People Over Profit: Values-Based & Unorthodox Leadership Styles. The estimated speaking fee range to book Patrick Casale for your event is $10,000 - $20,000. Patrick Casale generally travels from Asheville, NC, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. Similar motivational celebrity speakers are Elena Agaragimova, Adam Markel, Matt Johnson, Jeremy Kingsley and Sherene McHenry, Ph.D., LPC. Contact All American Speakers for ratings, reviews, videos and information on scheduling Patrick Casale for an upcoming live or virtual event.

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