Michael Roizen is an American anesthesiologist and internist, an award-winning author and the chief wellness officer at the Cleveland Clinic. Roizen became famous for developing the RealAge concept and has authored or coauthored five number one New York Times best sellers.

Roizen completed a tour of duty in the Public Health Service and has 165 peer reviewed publications and 100 medical chapters, 14 US patents, started six companies, served on Food and Drug Administration (FDA) advisory committees for 16 years, and chaired an FDA advisory committee. He also co-invented a drug, methylnaltrexone (MTNX, trade name Relistor), and took it through phase 2 trials. In May 2008, methylnaltrexone received FDA approval for marketing in the United States.

Roizen is a Phi Beta Kappa graduate of Williams College and Alpha Omega Alpha graduate of the University of California–San Francisco School of Medicine. He performed his residency in internal medicine at Harvard's Beth Israel Hospital and completed Public Health Service at the National Institutes of Health in the laboratory of Irv Kopin and Nobel Prize winner Julius Axelrod. He is certified by both the American Boards of Internal Medicine and of Anesthesiology.

After nine years on the faculty at the University of California–San Francisco, he chaired the top-ten rated Department of Anesthesia and Critical Care at the University of Chicago. He then became Dean of the School of Medicine and Vice President for Biomedical Sciences at SUNY Upstate. After serving as CEO of the Biotechnology Research Corporation of Central New York, he accepted a position as Chair of the Anesthesiology Institute at Cleveland Clinic, responsible for over 180 operatories, 124 critical care beds, and 28 pain therapy intervention units. In 2007, Dr. Roizen was named Chief Wellness Officer at Cleveland Clinic, the first such position in a major healthcare institution in the United States. He also serves as Chairman of the Wellness Institute at Cleveland Clinic.

Dr. Roizen's first general audience book, RealAge: Are You as Young as You Can Be? became a #1 New York Times bestseller and was awarded the Best Wellness Book of 1999 by the Books for a Better Life Awards. RealAge has been translated into more than 20 languages and was #1 in four other countries, displacing Harry Potter for seven days as #1 on Amazon. Other books include the New York Times bestseller The RealAge Diet: Make Yourself Younger with What You Eat, written with Dr. John La Puma; Cooking the RealAge Way, also with Dr. La Puma.; and The RealAge Makeover. His book, YOU: The Owner's Manual, written with Health Corps founder Dr. Mehmet Oz, debuted in May 2005 and became a #1 New York Times bestseller. It was followed by the New York Times bestseller YOU: The Smart Patient. Their next book, YOU: On a Diet: the Owner's Manual for Waist Management, debuted at #1 on the New York Times Bestseller List. Their book, YOU Staying Young: the Owner's Manual for Extending Your Warranty also debuted at #1 on the New York Times Bestseller List.

Dr. Roizen has given over 1,400 lectures to professional medical groups and has been recognized with over 20 professional lectureships. He has appeared on The Oprah Winfrey Show, The Today Show, 20/20, CBN, CNN, CBS, Good Morning America, Canada AM, The Montel Williams Show, and Larry King Live, and has four PBS fundraising specials. His most recent two PBS specials, YOU on a Diet and Longevity Factors, have both received acclaim and widespread distribution as well. He and Mehmet Oz write a monthly column for Reader's Digest, a quarterly column for the nursing magazine Every Woman, and a daily newspaper column syndicated by King. He and Mehmet also record one hour a day of radio for Oprah and Friends on satellite radio and a cable network. He also has a two-hour 26-station Terrestrial show entitled: YOU The Owner's Manual Radio Show, live every Saturday. Dr. Roizen has been featured in Fortune, O, Glamour, Cosmopolitan, Good Housekeeping, Ladies' Home Journal, Biography, People, US Weekly, Men's Health, and Prevention.

Dr. Roizen still practices anesthesiology and internal medicine, using the RealAge metric to motivate his patients. He routinely takes patients at the Cleveland Clinic Wellness Institute who are in the midst of struggling with tobacco, heart, diabetic, or arthritic problems, and coaches them with simple (but persistent) lifestyle changes to be able to live, feel, and look years younger. He really enjoys getting them to throw away their medications when they no longer need them, but teaches the role of food and other simple steps in reversing disease processes. The Wellness Institute that he chairs includes Employee Health and Wellness, the Department of Preventive Medicine, Premium Access Programs, Disease Reversal and Integrative Medicine Programs, and the Wellness Public Policy and Community Support Programs of Cleveland Clinic. Cleveland Clinic Wellness institute aims to elevate preventive care and wellness as a core brand of Cleveland Clinic and a core value taught to patients and employees.

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