Academic Healthcare Leader & President of UCLA Health; CEO of UCLA Hospital System

Los Angeles, CA, USA
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Johnese Spisso Biography

Johnese Spisso is a leader in academic healthcare, serving as president of UCLA Health, CEO of the UCLA Hospital System, and associate vice chancellor of UCLA Health Sciences. With more than four decades of experience, Spisso oversees the operations of five hospitals and more than 300 clinics across Southern California, including Ronald Reagan UCLA Medical Center and the UCLA Health Homeless Healthcare Collaborative. Spisso has overseen the expansion of patient access through the addition of more than 100 clinics, the acquisition of UCLA West Valley Medical Center, and the implementation of programs addressing healthcare disparities, such as mobile medical services for homeless populations and the expansion of psychiatric care facilities.

Spisso began her career as a critical-care nurse and advanced through leadership roles at UC Davis Medical Center and UW Medicine, where she served as chief health system officer and vice president for medical affairs. Her expertise in trauma systems and healthcare leadership is reflected in her publications and frequent speaking engagements at national conferences. Spisso is recognized for her ability to lead complex organizations through periods of transformation and for her commitment to mentoring future healthcare leaders.

Spisso has received recognition including being named CEO of the Year by Los Angeles Business Journal, inclusion in Modern Healthcare’s lists of the "50 Most Influential Clinical Executives" and "Top 25 Women Leaders," and multiple awards for excellence in healthcare leadership. Spisso is a frequent speaker on healthcare innovation, access, and leadership, and is a prominent figure in academic medicine.

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Speaker profile last updated by AAE Talent Team on 08/14/2025.

Johnese Spisso Videos

PANEL: LA Hospital Leaders Innovating for Future Success

PANEL: LA Hospital Leaders Innovating for Future Success

https://tdg.ucla.edu/ A panel discussion with Hospital CEOs from our long-standing LABEST partners in the Los Angeles area, covering challenges,...

Becker's Healthcare Conference 2021 with Johnese Spisso

Becker's Healthcare Conference 2021 with Johnese Spisso

In a fireside chat with Rhoda Weiss, PhD (co-chair of Becker's Healthcare Conference), Johnese Spisso, RN, MPA (President, UCLA Health; CEO, UCLA...

UCLA Health President and CEO, Johnese Spisso’s Keynote Interview: Becker’s Healthcare Virtual Event

UCLA Health President and CEO, Johnese Spisso’s Keynote Interview: Becker’s Healthcare Virtual Event

Johnese Spisso, UCLA Health President and CEO of the UCLA Hospital System, recently sat down with Rhoda Weiss, PhD, to share her approach to leading...

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  • What topics does Johnese Spisso speak about?

    Johnese Spisso is a keynote speaker and industry expert whose speaking topics include Diversity & Inclusion, Executive Leadership, Female Leadership, Healthcare, Influential Women, Innovation, Leadership
  • Where does Johnese Spisso travel from?

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Johnese Spisso is a keynote speaker and industry expert who speaks on a wide range of topics. The estimated speaking fee range to book Johnese Spisso for your event is available upon request. Johnese Spisso generally travels from Los Angeles, CA, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. Similar motivational celebrity speakers are Carina Edwards, Emma Walmsley, Alexandra Drane, Sallie Krawcheck and Helene D. Gayle. Contact All American Speakers for ratings, reviews, videos and information on scheduling Johnese Spisso for an upcoming live or virtual event.

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