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Kellie Smith

Kellie Smith

Assistant Professor of Oncology; Recipient of Lung Cancer Foundation of America Grant; Expert in Immunotherapy

Travels From Travels From:
Baltimore, MD, USA
Speaking Fee Speaking Fee:
Live Event: $5,000 - $10,000
Virtual Event: $5,000 - $10,000
More Fee Info
Categories Categories:
Categories Categories:
Cancer, Medicine, Research & Exploration, Science
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Kellie Smith Biography

Dr. Smith, a Baltimore, MD native, completed her doctoral work at the University of Pittsburgh School of Medicine under the direction of Dr. Charles R. Rinaldo with a focus on T cell immunology and immunotherapy. During her fellowship training at Johns Hopkins, she worked under the mentorship of Dr. Drew M. Pardoll identifying the correlates of response to anti-PD-1 immunotherapy in patients with multiple tumor histologies with a specific emphasis on early and advanced-stage non-small cell lung cancer. She joined the faculty in early 2016 and has since collaborated with many clinicians within Johns Hopkins and at outside institutions on immunotherapy clinical trials aimed at improving treatment options, preventing disease recurrence, and understanding the predictors of response to treatment in both early and advanced-stage disease.

Dr. Smith’s group has developed a novel patent-pending technique to detect and monitor anti-tumor T cells using a simple liquid biopsy approach. This technique, termed MANAFEST (mutation associated neoantigen functional expansion of specific T-cells), is being used in 8 clinical trials and at 5 different research institutions and biotech companies to monitor responses to mutation associated neoantigens, endogenous retroviruses, tumor associated antigens, and viral antigens. This approach has been used to identify neoantigen-specific responses in lung cancer patients with acquired resistance to checkpoint blockade and in colorectal cancer patients with durable clinical benefit to anti-PD-1. More recently, this approach was able to show for the first time that neoantigen-specific T cells are amplified in the periphery following neoadjuvant PD-1 blockade and that these responses may facilitate tumor regression and prevent relapse after surgical resection.

Ongoing work includes linking the MANAFEST assay with single cell sequencing technologies to ascertain the intratumoral phenotype of anti-tumor T cells, with a specific interest in how checkpoint blockade treatment regimens augment anti-tumor immunity. This work will elucidate prognostic biomarkers of response and resistance to checkpoint blockade and will help stratify patients most likely to benefit from these treatments.

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Speaker profile last updated by AAE Talent Team on 01/01/2025.

Kellie Smith Videos

  • Kellie Smith: Tumor Reactive T cell Functional Programming in Human Cancer
    Kellie Smith: Tumor Reactive T cell Functional Programming in Human Cancer
  • In-Depth Immunotherapy for Lung Cancer | Hope With Answers
    In-Depth Immunotherapy for Lung Cancer | Hope With Answers
    Discover in-depth information about immunotherapy for lung cancer through this conversation between Dr. Kellie Smith of John Hopkins and patient...
  • Dr. Kellie Smith: LCFA Grants and Research in immunotherapy for early stage
    Dr. Kellie Smith: LCFA Grants and Research in immunotherapy for early stage
    Dr. Kellie Smith, 2016 LCFA Grant Recipient, on what the grant means to her research into immunotherapy for early stage lung cancer patients.
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FAQs on booking Kellie Smith

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  • What are the speaker fees for Kellie Smith

    Speaking fees for Kellie Smith, or any other speakers and celebrities, are determined based on a number of factors and may change without notice. The estimated fees to book Kellie Smith are for live events and for virtual events. For the most current speaking fee to hire Kellie Smith, click the Check Availability button above and complete the form on this page, or call our office at 1.800.698.2536 to speak directly with an experienced booking agent.

  • What topics does Kellie Smith speak about?

    Kellie Smith is a keynote speaker and industry expert whose speaking topics include Cancer, Medicine, Research & Exploration, Science.

  • Where does Kellie Smith travel from?

    Kellie Smith generally travels from Baltimore, MD, USA, but can be booked for private corporate events, personal appearances, keynote speeches, or other performances. For more details, please contact an AAE Booking agent.

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Kellie Smith is a keynote speaker and industry expert who speaks on a wide range of topics . The estimated speaking fee range to book Kellie Smith for your event is $5,000 - $10,000. Kellie Smith generally travels from Baltimore, MD, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. Similar motivational celebrity speakers are Dr. Daniel J. Spakowicz, Alice Berger, Ph.D., Haiying Cheng, MD, PhD, Dr. Jarushka Naidoo and Dr. Zoltan Lohinai. Contact All American Speakers for ratings, reviews, videos and information on scheduling Kellie Smith for an upcoming live or virtual event.

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