Chief Operating Officer for the American Medical Association; Former Chief Medical Officer at Walmart Health & Wellness

Boston, MA, USA
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John Wigneswaran Biography

John Wigneswaran, MD, MBA, is a physician-executive whose career spans nearly three decades at the intersection of clinical medicine and large-scale healthcare operations. Wigneswaran graduated from Tufts University School of Medicine and earned an MBA from MIT Sloan School of Management. He completed undergraduate studies at Cornell University, a nephrology fellowship at New York-Presbyterian/Weill Cornell Medical Center, and an internal medicine residency at Rhode Island Hospital/Brown University. Wigneswaran has more than a decade of clinical experience as a practicing nephrologist and served as a renal fellowship preceptor in the Division of Nephrology at Rhode Island Hospital/Brown University.

Wigneswaran’s transition from bedside medicine to executive leadership included roles across the healthcare industry. Early in his career, he served as director of medical affairs for Scios Inc., a heart failure company, contributing to the clinical team’s achievement of significant sales and its acquisition by Johnson & Johnson. He subsequently held positions in the pharmaceutical, medical device, pharmacy benefit management, and healthcare services industries, including roles at Express Scripts/Cigna, DaVita, Fresenius Medical Care, Gambro, Nephroceuticals, and Johnson & Johnson. He served as chief medical officer of pharmacy-benefits manager Express Scripts, which was acquired by Cigna.

At Walmart, Wigneswaran served as chief medical officer for Health & Wellness, where he was responsible for building a national quality and safety framework for the company’s pharmacies and clinics. Previously, as chief clinical officer for Optum Rx, a division of UnitedHealth Group, he oversaw clinical services for prescription benefits, managed clinical product development, and directed specialty medication strategy. His appointment to the National Kidney Foundation board of directors during this period reflects his commitment to patient advocacy. Wigneswaran has stated that he was drawn to nephrology because of the unique needs of the patient population, particularly those in underserved communities, and the opportunity to make an impact as an advocate.

The American Medical Association appointed Wigneswaran as chief operating officer. In this role, he oversees business operations, health solutions, information technology, AMA Insurance, and JAMA Publishing, and provides executive leadership for new ventures and innovation initiatives for the nation’s largest physician organization. Wigneswaran brings experience from executive positions at Walmart, UnitedHealth Group, Cigna/Express Scripts, and Fresenius Medical Care, where he led core business operations across payer, provider, pharmaceutical, and retail sectors. His background combines frontline clinical experience with enterprise-level leadership, positioning him as a knowledgeable voice in healthcare management, physician leadership, and health system innovation.

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Speaker profile last updated by AAE Talent Team on 07/01/2026.

John Wigneswaran Videos

Future Trends and Insights Impacting Drug Spend

Future Trends and Insights Impacting Drug Spend

Hear from Marly Arbuckle, VP of Trend Intelligence, and Dr. John Wigneswaran, Chief Clinical Officer at Optum Rx.

Human-Centered Care

Human-Centered Care

We're grateful to have passionate people on our team like Dr. John Wigneswaran. Wig, as he likes to be called, is our Chief Medical Officer and...

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  • What topics does John Wigneswaran speak about?

    John Wigneswaran is a keynote speaker and industry expert whose speaking topics include Digital Health, Futurism, Healthcare, Innovation, Medicine, Public Health
  • Where does John Wigneswaran travel from?

    John Wigneswaran generally travels from Boston, MA, USA, but can be booked for private corporate events, personal appearances, keynote speeches, or other performances. For more details, please contact an AAE Booking agent.
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John Wigneswaran is a keynote speaker and industry expert who speaks on a wide range of topics. The estimated speaking fee range to book John Wigneswaran for your event is available upon request. John Wigneswaran generally travels from Boston, MA, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. Similar motivational celebrity speakers are Bobby Mukkamala, Dr. Joel Selanikio, Ben Goldacre, Ricky Choi and Kimberly Sterling. Contact All American Speakers for ratings, reviews, videos and information on scheduling John Wigneswaran for an upcoming live or virtual event.

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