Top-Rated Speakers Bureau and Entertainment Booking Agency for Corporate Meetings and Business Events. Book an AAE Speaker Today.
Top-Rated Speakers Bureau and Entertainment Booking Agency for Corporate Meetings and Business Events. Book an AAE Speaker Today.
Click to Open Search Bar

Gregory Petsko

My research is concerned with the three-dimensional structures of proteins and their biochemical functions. Most of my work is done in collaboration with Prof. Dagmar Ringe; we share facilities, students, and a number of projects.

REQUEST BOOKING INFORMATION

Gregory Petsko Biography

My research is concerned with the three-dimensional structures of proteins and their biochemical functions. Most of my work is done in collaboration with Prof. Dagmar Ringe; we share facilities, students, and a number of projects. The tools used by our group are X-ray crystallography, molecular biology (especially site-directed mutagenesis), yeast genetics, organic synthesis, enzyme kinetics and molecular dynamics calculations. These methods are being applied to several general problems; the ones I am most involved with include: the structural basis for efficient enzymic catalysis of proton and hydride transfer; the role of the metal ions in bridged bimetalloenzyme active sites; direct visualization of proteins in action by time-resolved protein crystallography; the evolution of new enzyme activities from old ones; and the biology of the quiescent state in eukaryotic cells.

figure1In some of these projects, we are trying to understand the structural basis for the catalytic power of the enzymes triose phosphate isomerase, xylose isomerase, mandelate racemase, aminopeptidase, mutarotase and ketosteroid isomerase. For all of them, structural information is being used to guide site-directed mutagenesis of the active site residues and combined quantum mechanics/molecular mechanics simulations of the catalytic reaction.

Protein crystallography is normally a static tool and cannot be used to follow biological reactions in real time. We have been involved in the development of new diffraction techniques, including Laue diffraction, that are capable of recording entire protein crystal data sets in a millisecond. When combined with low-temperature techniques, such methods can be used to determine the structures of catalytic intermediates.

A new area of research in the laboratory is the use of yeast genetics and biochemical techniques to study the quiscent state of eukaryotic cells. We have recently shown that cells arrest their cell cycle in G1 and then exit to the G0 state when unfolded proteins accumulate in the cytoplasm. Accompanying these cell cycle changes is a global shutdown in ribosomal protein expression. This process is partly under control of the heat shock transcription factor HSF. Another project that uses yeast genetics and molecular biology is our attempt to design a new metabolic pathway that will allow yeast to grow on lactonitrile or lactamide as sole carbon sources. The enzymes in this new pathway are being engineered from enzymes of the mandelonitrile pathway in bacteria by a combination of structure-directed and random mutagenesis.

Videos
Books
Gregory Petsko in Genome Biology: The first 10 years

Gregory Petsko in Genome Biology: The first 10 years

FAQs
  • How do I book Gregory Petsko to speak at my event?

    Our experienced booking agents have successfully helped clients around the world secure speakers like Gregory Petsko for speaking engagements, personal appearances, product endorsements, or corporate entertainment since 2002. Click the Check Availability button above and complete the form on this page to check availability for Gregory Petsko, or call our office at 1.800.698.2536 to discuss your upcoming event. One of our experienced agents will be happy to help you get speaking fee information and check availability for Gregory Petsko or any other speaker of your choice.
  • What are the speaker fees for Gregory Petsko

    Speaking fees for Gregory Petsko, or any other speakers and celebrities, are determined based on a number of factors and may change without notice. The estimated fees to book Gregory Petsko are available upon request for live events and available upon request for virtual events. For the most current speaking fee to hire Gregory Petsko, click the Check Availability button above and complete the form on this page, or call our office at 1.800.698.2536 to speak directly with an experienced booking agent.
  • What topics does Gregory Petsko speak about?

    Gregory Petsko is a keynote speaker and industry expert whose speaking topics include Education, Health and Wellness, Innovation, Science and Technology, Technology Speakers, TED, University Speakers.
  • Where does Gregory Petsko travel from?

    Gregory Petsko generally travels from Massachusetts, USA, but can be booked for private corporate events, personal appearances, keynote speeches, or other performances. For more details, please contact an AAE Booking agent.
  • Who is Gregory Petsko’s agent?

    AAE Speakers Bureau has successfully booked keynote speakers like Gregory Petsko for clients worldwide since 2002. As a full-service speaker booking agency, we have access to virtually any speaker or celebrity in the world. Our agents are happy and able to submit an offer to the speaker or celebrity of your choice, letting you benefit from our reputation and long-standing relationships in the industry. Please click the Check Availability button above and complete the form on this page including the details of your event, or call our office at 1.800.698.2536, and one of our agents will assist you to book Gregory Petsko for your next private or corporate function.
  • What is a full-service speaker booking agency?

    AAE Speakers Bureau is a full-service speaker booking agency, meaning we can completely manage the speaker’s or celebrity’s engagement with your organization from the time of booking your speaker through the event’s completion. We provide all of the services you need to host Gregory Petsko or any other speaker of your choice, including offer negotiation, contractual assistance, accounting and billing, and event speaker travel and logistics services. When you book a speaker with us, we manage the process of hosting a speaker for you as an extension of your team. Our goal is to give our clients peace of mind and a best-in-class service experience when booking a speaker with us.
  • Why is AAE Speakers Bureau different from other booking agencies?

    If you’re looking for the best, unbiased speaker recommendations, paired with a top-notch customer service experience, you’re in the right place. At AAE Speakers Bureau, we exclusively represent the interests of our clients - professional organizations, companies, universities, and associations. We intentionally do not represent the speakers we feature or book. That is so we can present our clients with the broadest and best performing set of speaker options in the market today, and we can make these recommendations without any obligation to promote a specific speaker over another. This is why when our agents suggest a speaker for your event, you can be assured that they are of the highest quality with a history of proven success with our other clients.
Check Availability

Tell us about your event!

During normal business hours, we respond to most inquiries within 4 hours.

Users also viewed these speakers:

This website is a resource for event professionals and strives to provide the most comprehensive catalog of thought leaders and industry experts to consider for speaking engagements. A listing or profile on this website does not imply an agency affiliation or endorsement by the talent.

All American Entertainment (AAE) exclusively represents the interests of talent buyers, and does not claim to be the agency or management for any speaker or artist on this site. AAE is a talent booking agency for paid events only. We do not handle requests for donation of time or media requests for interviews, and cannot provide celebrity contact information.

If you are the talent and wish to request a profile update or removal from our online directory, please submit a profile request form.

My research is concerned with the three-dimensional structures of proteins and their biochemical functions. Most of my work is done in collaboration with Prof. Dagmar Ringe; we share facilities, students, and a number of projects.

Travels From:
Massachusetts, USA
Speaking Fee:

Gregory Petsko Biography

My research is concerned with the three-dimensional structures of proteins and their biochemical functions. Most of my work is done in collaboration with Prof. Dagmar Ringe; we share facilities, students, and a number of projects. The tools used by our group are X-ray crystallography, molecular biology (especially site-directed mutagenesis), yeast genetics, organic synthesis, enzyme kinetics and molecular dynamics calculations. These methods are being applied to several general problems; the ones I am most involved with include: the structural basis for efficient enzymic catalysis of proton and hydride transfer; the role of the metal ions in bridged bimetalloenzyme active sites; direct visualization of proteins in action by time-resolved protein crystallography; the evolution of new enzyme activities from old ones; and the biology of the quiescent state in eukaryotic cells.

figure1In some of these projects, we are trying to understand the structural basis for the catalytic power of the enzymes triose phosphate isomerase, xylose isomerase, mandelate racemase, aminopeptidase, mutarotase and ketosteroid isomerase. For all of them, structural information is being used to guide site-directed mutagenesis of the active site residues and combined quantum mechanics/molecular mechanics simulations of the catalytic reaction.

Protein crystallography is normally a static tool and cannot be used to follow biological reactions in real time. We have been involved in the development of new diffraction techniques, including Laue diffraction, that are capable of recording entire protein crystal data sets in a millisecond. When combined with low-temperature techniques, such methods can be used to determine the structures of catalytic intermediates.

A new area of research in the laboratory is the use of yeast genetics and biochemical techniques to study the quiscent state of eukaryotic cells. We have recently shown that cells arrest their cell cycle in G1 and then exit to the G0 state when unfolded proteins accumulate in the cytoplasm. Accompanying these cell cycle changes is a global shutdown in ribosomal protein expression. This process is partly under control of the heat shock transcription factor HSF. Another project that uses yeast genetics and molecular biology is our attempt to design a new metabolic pathway that will allow yeast to grow on lactonitrile or lactamide as sole carbon sources. The enzymes in this new pathway are being engineered from enzymes of the mandelonitrile pathway in bacteria by a combination of structure-directed and random mutagenesis.

Gregory Petsko Videos

  • Gregory Petsko at TEDMED 2012
  • Greg Petsko: 15 Million in U.S. with Alzheimer's by 2050
  • Gregory Petsko (Brandeis/Weill Cornell Medical Center): The Post ...

Gregory Petsko Books

FAQs on booking Gregory Petsko

  • How do I book Gregory Petsko to speak at my event?

    Our experienced booking agents have successfully helped clients around the world secure speakers like Gregory Petsko for speaking engagements, personal appearances, product endorsements, or corporate entertainment since 2002. Click the Check Availability button above and complete the form on this page to check availability for Gregory Petsko, or call our office at 1.800.698.2536 to discuss your upcoming event. One of our experienced agents will be happy to help you get speaking fee information and check availability for Gregory Petsko or any other speaker of your choice.
  • What are the speaker fees for Gregory Petsko

    Speaking fees for Gregory Petsko, or any other speakers and celebrities, are determined based on a number of factors and may change without notice. The estimated fees to book Gregory Petsko are available upon request for live events and available upon request for virtual events. For the most current speaking fee to hire Gregory Petsko, click the Check Availability button above and complete the form on this page, or call our office at 1.800.698.2536 to speak directly with an experienced booking agent.
  • What topics does Gregory Petsko speak about?

    Gregory Petsko is a keynote speaker and industry expert whose speaking topics include Education, Health and Wellness, Innovation, Science and Technology, Technology Speakers, TED, University Speakers.
  • Where does Gregory Petsko travel from?

    Gregory Petsko generally travels from Massachusetts, USA, but can be booked for private corporate events, personal appearances, keynote speeches, or other performances. For more details, please contact an AAE Booking agent.
  • Who is Gregory Petsko’s agent?

    AAE Speakers Bureau has successfully booked keynote speakers like Gregory Petsko for clients worldwide since 2002. As a full-service speaker booking agency, we have access to virtually any speaker or celebrity in the world. Our agents are happy and able to submit an offer to the speaker or celebrity of your choice, letting you benefit from our reputation and long-standing relationships in the industry. Please click the Check Availability button above and complete the form on this page including the details of your event, or call our office at 1.800.698.2536, and one of our agents will assist you to book Gregory Petsko for your next private or corporate function.
  • What is a full-service speaker booking agency?

    AAE Speakers Bureau is a full-service speaker booking agency, meaning we can completely manage the speaker’s or celebrity’s engagement with your organization from the time of booking your speaker through the event’s completion. We provide all of the services you need to host Gregory Petsko or any other speaker of your choice, including offer negotiation, contractual assistance, accounting and billing, and event speaker travel and logistics services. When you book a speaker with us, we manage the process of hosting a speaker for you as an extension of your team. Our goal is to give our clients peace of mind and a best-in-class service experience when booking a speaker with us.
  • Why is AAE Speakers Bureau different from other booking agencies?

    If you’re looking for the best, unbiased speaker recommendations, paired with a top-notch customer service experience, you’re in the right place. At AAE Speakers Bureau, we exclusively represent the interests of our clients - professional organizations, companies, universities, and associations. We intentionally do not represent the speakers we feature or book. That is so we can present our clients with the broadest and best performing set of speaker options in the market today, and we can make these recommendations without any obligation to promote a specific speaker over another. This is why when our agents suggest a speaker for your event, you can be assured that they are of the highest quality with a history of proven success with our other clients.

Gregory Petsko is a keynote speaker and industry expert who speaks on a wide range of topics . The estimated speaking fee range to book Gregory Petsko for your event is available upon request. Gregory Petsko generally travels from MA, USA and can be booked for (private) corporate events, personal appearances, keynote speeches, or other performances. Similar motivational celebrity speakers are Jon Bergmann, David Houle, Bill Gates, Jeffrey Kluger and Clay Shirky. Contact All American Speakers for ratings, reviews, videos and information on scheduling Gregory Petsko for an upcoming live or virtual event.

Gregory Petsko Speaker Videos

  • Gregory Petsko at TEDMED 2012
    Greg Petsko: 15 Million in U.S. with Alzheimer's by 2050
  • Gregory Petsko (Brandeis/Weill Cornell Medical Center): The Post ...

Tell us about your event!

During normal business hours, we respond to most inquiries within 4 hours.

  • Customized Service

    Our agents find the right fit for your event

  • Unparalleled Database

    Full access to all speakers & celebrities

  • One Stop Shopping

    A reliable and unbiased point of contact

  • Logistics Management

    Your personal Logistics Manager who takes care of all event details

Speakers Similar to Gregory Petsko

This website is a resource for event professionals and strives to provide the most comprehensive catalog of thought leaders and industry experts to consider for speaking engagements. A listing or profile on this website does not imply an agency affiliation or endorsement by the talent.

All American Entertainment (AAE) exclusively represents the interests of talent buyers, and does not claim to be the agency or management for any speaker or artist on this site. AAE is a talent booking agency for paid events only. We do not handle requests for donation of time or media requests for interviews, and cannot provide celebrity contact information.

If you are the talent and wish to request a profile update or removal from our online directory, please submit a profile request form.

TOP