Bradley Cooper was born in Philadelphia and grew up in nearby Jenkintown, PA. While attending Germantown Academy, Cooper worked at the Philadelphia Daily News. After graduating from Germantown Academy in 1993, he attended Villanova University for his freshman year, then transferred to Georgetown University, from which he graduated with honors with a BA in English in 1997. Cooper became fluent in French at Georgetown and spent six months as an exchange student in Aix-en-Provence, France. Later in 2000, he received an MFA in acting from Actors Studio Drama School at The New School in New York City.

Cooper began his professional acting career on the television series "Sex and the City" in 1999 and also served as a presenter for "Globe Trekker." After his film debut in "Wet Hot American Summer" in 2001, Cooper landed his role as Will Tippin in the successful television drama "Alias." He returned twice to "Alias" as a guest star after leaving the show in 2003, and he also guest-starred on the TV series "Miss Match" in the same year.

Cooper played the part of cowboy and race horse trainer Morgan Murphy in the TV movie "The Last Cowboy," which aired on the Hallmark Channel on January 17, 2003. He also co-starred in the ABC Family film "I Want to Marry Ryan Banks" with Jason Priestley and appeared as a regular guest star in the WB series "Jack & Bobby." He played the popular villain Sack Lodge in the hit comedy "Wedding Crashers" and appeared in the film "Failure to Launch" as a friend of Matthew McConaughey's character. Cooper played the lead role in the Fox sitcom "Kitchen Confidential," based on a memoir by chef Anthony Bourdain, which debuted in September 2005.

In March 2006, Cooper starred in "Three Days of Rain" on Broadway with Julia Roberts and Paul Rudd at the Bernard B. Jacobs Theater. Cooper also appeared on stage as Jake in the 2008 production of Theresa Rebeck's play "The Understudy" at the Williamstown Theatre Festival alongside Kristen Johnston.

In 2007, Cooper starred in Season 5 of "Nip/Tuck" as Aidan Stone, a television star on the fictional show "Hearts 'N Scalpels." He also starred in "Yes Man" with Jim Carrey and in "The Rocker" with Rainn Wilson in 2008. On February 7, 2009, Cooper hosted "Saturday Night Live" with musical guest TV on the Radio. In 2009, Cooper starred in the films "He's Just Not That into You," "Case 39" and "The Hangover," which was a financial success and opened first at the box office in the United States and grossed over $467 million worldwide.

In October 2009, Cooper received the Hollywood Comedy Award at the 13th Annual Hollywood Film Festival and Hollywood Awards. In 2010, Cooper appeared in two films. He appeared in the ensemble romantic comedy "Valentine's Day," directed by Garry Marshall. He then played the role of Templeton "Faceman" Peck in the feature film version of "The A-Team."

In 2011, Cooper starred in the techno-thriller "Limitless," based on the 2001 novel "The Dark Fields" by Alan Glynn, and the comedy sequel "The Hangover Part II." In September 2011, GQ UK presented Cooper with the "International Man of the Year" award. On November 16, 2011, People magazine named him Sexiest Man Alive.

In 2012, he appeared in the drama "The Words," and David O. Russell's "Silver Linings Playbook," an adaptation of Matthew Quick's serio-comic novel, with Robert De Niro and Jennifer Lawrence. He starred in "The Place Beyond the Pines" as a police officer.

In 2013, Cooper appeared in the final installment of "The Hangover" series, "The Hangover Part III." Cooper's other projects include "American Hustle," "American Sniper" and "Guardians of the Galaxy." In the summer of 2015, Cooper starred in the Netflix original comedy series, "Wet Hot American Summer: First Day of Camp," as Ben. In 2014, he portrayed Joseph Merrick in a Broadway revival of The Elephant Man, garnering a nomination for the Tony Award for Best Actor in a Play, and began voicing Rocket Raccoon in the Marvel Cinematic Universe. In 2018, Cooper produced, wrote, directed and starred in a remake of the musical romance A Star Is Born. He earned three Oscar nominations for the film, as well as a BAFTA Award and two Grammys for his contributions to its U.S. Billboard 200 number one soundtrack and its chart-topping lead single "Shallow". He gained another Academy Award nomination for producing Joker (2019).

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