Jack Anderson was born in Long Beach, California, in 1922. Anderson was brought up in Salt Lake City and served two years as a Mormon missionary. His journalistic career when he began writing for his local newspaper, The Murray Eagle. At eighteen he joined the Salt Lake Tribune but during the Second World War he served in China. This included fighting the Japanese with a band of Chinese guerrillas. He also worked on the Shanghai edition of Stars and Stripes.

In 1947 Anderson he became a national journalist when he was recruited by Drew Pearson to work with him on The Washington Post.

Pearson and Anderson were always willing to expose the corrupt activities of politicians. Howard Hughes leaked information to Pearson that Owen Brewster, chairman of the Senate War Investigating Committee, was being paid by Pan American Airways (Pan Am) to persuade the United States government to set up an official worldwide monopoly under its control. Part of this plan was to force all existing American carriers with overseas operations to close down or merge with Pan Am. As the owner of Trans World Airlines, Hughes posed a serious threat to this plan. Hughes claimed that Brewster had approached him and suggested he merge Trans World with Pan Am.

Pearson and Jack Anderson began a campaign against Brewster. They reported that Pan Am had provided Bewster with free flights to Hobe Sound, Florida, where he stayed free of charge at the holiday home of Pan Am Vice President Sam Pryor. As a result of this campaign Bewster lost his seat in Congress.

In 1963 Senator John Williams of Delaware began investigating the activities of Bobby Baker. As a result of his work, Baker resigned as the secretary to Lyndon B. Johnson on 9th October, 1963. During his investigations Williams met Don B. Reynolds and persuaded him to appear before a secret session of the Senate Rules Committee.

Reynolds told B. Everett Jordan and his committee on 22nd November, 1963, that Johnson had demanded that he provided kickbacks in return for him agreeing to this life insurance policy. This included a $585 Magnavox stereo. Reynolds also had to pay for $1,200 worth of advertising on KTBC, Johnson's television station in Austin. Reynolds had paperwork for this transaction including a delivery note that indicated the stereo had been sent to the home of Johnson.

Reynolds also told of seeing a suitcase full of money which Bobby Baker described as a "$100,000 payoff to Johnson for his role in securing the Fort Worth TFX contract". His testimony came to an end when news arrived that President John F. Kennedy had been assassinated.

As soon as Johnson became president he contacted B. Everett Jordan to see if there was any chance of stopping this information being published. Jordan replied that he would do what he could but warned Johnson that some members of the committee wanted Reynold's testimony to be released to the public. On 6th December, 1963, Jordan spoke to Johnson on the telephone and said he was doing what he could to suppress the story because " it might spread (to) a place where we don't want it spread."

Abe Fortas, a lawyer who represented both Lyndon B. Johnson and Bobby Baker, worked behind the scenes in an effort to keep this information from the public. Johnson also arranged for a smear campaign to be organized against Reynolds. To help him do this J. Edgar Hoover passed to Johnson the FBI file on Reynolds.

On 17th January, 1964, the Senate Rules Committee voted to release to the public Reynolds' secret testimony. Johnson responded by leaking information from Reynolds' FBI file to Anderson and Drew Pearson. On 5th February, 1964, the Washington Post reported that Reynolds had lied about his academic success at West Point. The article also claimed that Reynolds had been a supporter of Joseph McCarthy and had accused business rivals of being secret members of the American Communist Party. It was also revealed that Reynolds had made anti-Semitic remarks while in Berlin in 1953.

In 1966 attempts were made to deport Johnny Roselli as an illegal alien. Roselli moved to Los Angeles where he went into early retirement. It was at this time he told attorney, Edward Morgan: "The last of the sniper teams dispatched by Robert Kennedy in 1963 to assassinate Fidel Castro were captured in Havana. Under torture they broke and confessed to being sponsored by the CIA and the US government. At that point, Castro remarked that, 'If that was the way President Kennedy wanted it, Cuba could engage in the same tactics'. The result was that Castro infiltrated teams of snipers into the US to kill Kennedy".

Morgan took the story to Anderson and Drew Pearson. The story was then passed on to Earl Warren. He did not want anything to do with it and so the information was then passed to the FBI. When they failed to investigate the story Anderson wrote an article entitled "President Johnson is sitting on a political H-bomb" about Roselli's story. It has been suggested that Roselli started this story at the request of his friends in the Central Intelligence Agency in order to divert attention from the investigation being carried out by Jim Garrison.

On the death of Drew Pearson in 1969, Anderson took over his Merry-Go-Round column. Co-written with Jan Muller, the column was distributed to more than 400 newspapers. Anderson and Muller also wrote the Jack Anderson Confidential, an in-depth monthly newsletter.

Anderson has achieved many important stories including the discovery that Central Intelligence Agency plot to kill Fidel Castro. In 1972 Anderson won the Pulitzer Prize for his journalism. The following year his book, The Anderson Tapes, dealt with the activities of Richard Nixon and J. Edgar Hoover.

Anderson interviewed Johnny Roselli just before he was murdered. On 7th September, 1976, the newspaper reported Roselli as saying : "When Oswald was picked up, the underworld conspirators feared he would crack and disclose information that might lead to them. This almost certainly would have brought a massive U.S. crackdown on the Mafia. So Jack Ruby was ordered to eliminate Oswald."

Anderson's autobiography, Confessions of a Muckraker, was published in 1979. Other books by Anderson include The Washington Money-Go-Round (1997) and Peace, War and Politics: An Eyewitness Account (1999).

Suffering from Parkinson's disease, Jack Anderson retired from journalism in July, 2004.